General Western Blot Reagents
Abcam BCA disodium salt, protein concentration determination reagent, 25G
MW 388.3 g/mol, Purity >98%. Cu(I)-specific colorimetric reagent used for measuring protein concentration. Proteins reduce alkaline Cu(II) to Cu(I) which complexes with BCA to form a purple complex. Absorbance at 562nm is directly proportional to protein concentration.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Rosiglitazone potassium salt, PPARgamma agonist, 50MG
MW 395.5 Da, Purity >99%. Potent, selective PPARγ agonist (Kd = 43 nM, PPARγ ligand binding domain). Activates PPARγ expression (EC₅₀ = 1 μM). Shows antidiabetic and hypoglycemic effects in vivo. Orally active. Water soluble.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Diltiazem (mM/ml), L-type Ca2+ channel antagonist, 100MM_ML
MW 451 Da, Purity >99%. L-type Ca2+ channel antagonist. Coronary vasodilator. Soluble in 1 ml water to give specified mM/ml concentration.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 6-IAF (6-Iodoacetamidofluorescein), Thiol-reactive fluorescent label, 50MG
MW 515.3 Da, Purity >95%. Thiol-reactive fluorescent label. Acts as an acceptor fluorophore in FRET studies with excitation and emission maxima of 347 and 530 nm respectively. 6-IATR (ab145010) derivative. Labels actin, microtubule-associated proteins and histones.
The product is subject to the following: Abcam Restricted Use Statement
Abcam N-(3-O x ododecanoyl)-L-homoserine lactone, involved in quorum sensing, 10MG
MW 297.39 g/mol, Purity >98%. Autoinducer involved in quorum sensing by Pseudomonas aeruginosa. Member of N-acyl-homoserine lactone (AHL) family that regulate gene expression in gram-negative bacteria and are involved in the processes of bacterial quorum sensing.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 4-P-PDOT, MT2 selective melatonin receptor antagonist, 50MG
MW 279.4 Da, Purity >99%. MT2 selective melatonin receptor antagonist (Ki values are 0.46 and 56 nM for MT2 and MT1 respectively). Counteracts melatonin-mediated ERK- and Nrf2-related antioxidant potential *in vivo.* Centrally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam DCIA, Fluorescent thiol-reactive neutral probe, 10MG
MW 490.33 g/mol, Purity >85%. Fluorescent thiol-reactive neutral probe. Self-quenching until it reacts with thiol groups and regains its strong fluorescence.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 4,4prime-Diazido-2,2prime-stilbenedisulfonic acid disodium salt tetrahydrate, 10G
MW 538.42 g/mol, Purity >99%. Reagent for enzyme immobilisation on fibroin by photo-crosslinking; water-soluble over a wide pH range.
The product is subject to the following: Abcam Restricted Use Statement
Abcam N-Palmitoyl phosphatidylethanolamine, Endogenous lipid anorectic hormone, 5MG
MW 930.4 g/mol, Purity >98%. Endogenous lipid which significantly reduced food intake in a dose-dependent fashion when administered to rats and mice without causing taste aversion. Found to enter the brain (concentrating in the hypothalamus) when administered systemically and also reduced food intake when infused intracerebroventricularly (nanomolar concentrations), suggesting that mediation of effects is via the CNS. Chronic infusion resulted in a reduction of both food intake and body weight, suggesting that NAPE and long-acting NAPE analogs may be novel therapeutic targets for the treatment of obesity.
The product is subject to the following: Abcam Restricted Use Statement
Abcam N-He x anoyl-L-homoserine lactone, involved in quorum sensing, 50MG
MW 199.3 g/mol, Purity >98%. Autoinducer involved in quorum sensing. Member of N-acyl-homoserine lactone (AHL) family that regulate gene expression in gram-negative bacteria and are involved in the processes of bacterial quorum sensing.
The product is subject to the following: Abcam Restricted Use Statement
Abcam BDSF (cis-2-dodecenoic acid), Diffusible fatty acid signal molecule, 10MG
MW 198.3 Da, Purity >95%. Diffusible fatty acid signal molecule. Acts as a bacterial virulence factor. Activates DSF-dependent responses. Inhibits germ tube formation in Candida albicans. Shows antifungal effects in vivo..
The product is subject to the following: Abcam Restricted Use Statement
Abcam Voriconazole (UK-109, 496), anti-fungal agent, 50MG
MW 349.31 Da, Purity >99%. Potent and broad-spectrum anti-fungal agent. Inhibits CYP450-dependent 14-α sterol demethylase, to interfere with ergosterol biosynthesis and inhibit fungal growth. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam AMN082 dihydrochloride, mGlu7 agonist, 10MG
MW 465.5 Da, Purity >98%. Potent, selective, orally active and brain penetrant mGlu7 receptor agonist. Potently inhibits cAMP accumulation and stimulates GTP binding (EC50 = 64-290 nM) in mGluR7 transfected cells. Selective over mGlu1, 2, 3, 4,5, 6, and 8, ionotropic receptors (up to 10 μM). Elevates plasma stress hormones *in vivo*. Induces mGlu7 receptor internalisation in dissociated hippocampal neurones.
The product is subject to the following: Abcam Restricted Use Statement
Abcam N-(3-Hydro x ydodecanoyl)-DL-homoserine lactone, Quorum sensing agent, 250MG
MW 299.41 g/mol, Purity >97%. Quorum sensing agent. Member of N-acyl-homoserine lactone (AHL) family that regulate gene expression in gram-negative bacteria and are involved in the processes of bacterial quorum sensing.
The product is subject to the following: Abcam Restricted Use Statement
Abcam AG 825, ErbB2 inhibitor, 10MG
MW 397.5 Da, Purity >96%. Selective ErbB2 inhibitor (IC₅₀ values are 0.15 and 19 μM at ErbB2 and ErbB1, respectively). Suppresses IL-6 induced STAT3 activation. Shows antiproliferative effects. Shows antitumor effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement